Pernessa C. Seele is an American immunologist and interfaith public health activist. She is the CEO and founder of the Balm in Gilead, Inc., a religious-based organization that provides support to people with AIDS and their families, as well as working for the prevention of HIV and AIDS. Through a cooperative agreement with the CDC, the Balm in Gilead, Inc. operates the Black Church HIV/AIDS National Technical Assistance Center. The Balm in Gilead, Inc., serves and connects 10,000 churches and 70 community organizations in the United States, some African nations, and the Caribbean.